Journal: Research and Practice in Thrombosis and Haemostasis
Article Title: Increased von Willebrand factor levels in polycythemia vera and phenotypic differences with essential thrombocythemia
doi: 10.1002/rth2.12315
Figure Lengend Snippet: Correlations between VWF:Ag and VWF:Act, FVIII, JAK2‐p.V617F, or erythrocytes in 48 patients with PV. (A) Correlation between VWF:Ag and VWF:Act levels. (B) Correlation between VWF:Ag and FVIII levels; (C) Correlation between VWF:Ag and JAK2‐p.V617F allelic burden; (D) Correlation between VWF:Ag and erythrocyte count; the rho and P values are indicated in each panel. FVIII, factor VIII; JAK2‐p.V617F: Janus kinase 2‐p.V617F; PV: polycythemia vera; VWF:Act, von Willebrand factor activity; VWF:Ag, von Willebrand factor antigen
Article Snippet: Briefly, genomic DNA obtained from peripheral blood mononuclear cells isolated from whole blood was amplified with ipsogen JAK2 MutaScreen RS kit (QIAGEN GmbH, Hilden, Germany) and analyzed by ABI PRISM 7900HT instruments (Applied Biosystems, Austin, TX, USA).
Techniques: Activity Assay